Ainsley Malone, a dietitian with the Nutrition Support Team at Mount Carmel West, published an article about glycemic control in Support Line.

Malone, A. (2008). Weight loss and asthma: A systematic review. Support Line, 30(5), 3–8.

Abstract:

Hyperglycemia is common in critically ill patients, primarily as a result of the stress response and its effects on metabolism. Over the past 10 years, mounting evidence has demonstrated adverse outcomes associated with hyperglycemia. Trials evaluating the use of insulin therapy to improve glucose control and affect patient outcomes have been conducted over the last 8 years. The landmark 2001 van den Berghe trial demonstrating improved hospital mortality with tight glycemic control has resulted in a significant practice change in many intensive care units. Recently, though, conflicting data on the benefits of tight glucose control on patient outcomes have been reported. In addition, the increased incidence of hypoglycemia with intensive insulin therapy is being recognized. This article reviews the research evaluating tight glycemic control in the critically ill patient, describes current national practice guidelines, and offers recommendations for practice.